MicroRNAs (miRNAs) are short (∼22 nucleotides) non-coding RNAs that play critical roles in many biological processes and diseases, including oncogenesis 1. miRNAs guide the silencing Argonaute protein ...

The experience-dependent development of neural circuits is essential for higher cognitive functions, and defects lead to severe neurodevelopmental disorders, including ASD 1. The ubiquitin E3 ligase ...

Declining brain and neurobiological function is arguably one of the most common features of human aging. The study of conserved aging processes as well as the characterization of various ...

Non-coding RNAs (ncRNAs) have emerged as critical regulators of transcription, epigenetic processes, and gene silencing, which make them ideal candidates for insight into molecular evolution and a ...

In the healthy mature artery, vascular cells, including endothelial cells, smooth muscle cells (SMCs), and fibroblasts are organized in different layers, performing specific functions. SMCs located in ...

Nucleoli have long been known as the sites of rRNA synthesis and processing and more recently for production of several long non-coding (lnc) RNAs that regulate rRNA transcription and other aspects of ...

#' the object of opened annotated GDS file, and the object from fitting the null model to analyze the association between a #' quantitative/dichotomous phenotype ...