Current methodologies for the detection of inducible Pluripotent Stem (iPS) reprogramming are either disruptive e.g. flow cytometry (FC) or low in throughput e.g. fluorescent microscopy (FM). Using ...

The iPS cells passed the standard barrage of tests for pluripotency, and microarray analyses demonstrated that these cells exhibited similar gene expression profiles to embryonic stem cells. The new ...

In 2006, Kyoto University’s Professor Yamanaka Shin’ya made a groundbreaking discovery: a method to reprogram ordinary body cells such as skin, nerve, or bone cells into a highly adaptable, ...

A modified version of iPS methodology, called interrupted reprogramming, allows for a highly controlled, potentially safer, and more cost-effective strategy for generating progenitor-like cells from ...

Cells that have been artificially reprogrammed into states similar to embryonic stem cells — known as induced pluripotent stem cells — can bear a memory of their previous history. An innovative method ...

In reading, a bookmark tells where you stopped. Cells use bookmarks too, specific proteins that help the cell remember what collection of genes needs to be turned on again after the brief halt of gene ...

The 2012 Nobel prize-winning discovery that ordinary cells could be coaxed to revert to their earliest pluripotent stage ushered in the era of ethical stem cell research. Suddenly, scientists can have ...

Today researchers are able to reprogram cells that are obtained from adult tissues to turn back in development into cells that resemble embryonic stem cells. These cells are called induced pluripotent ...

Researchers from Monash University in Melbourne and The University of Western Australia have demonstrated how a reprogramming method imitates embryonic epigenetic reset. Transient naive treatment (TNT ...

Within the vibrant environment of the GIBH - Max Planck Center for Regenerative Biomedicine, a team of scientists revealed the initial molecular mechanisms of factor-induced reprogramming of ...