The size of the membrane-bound nucleus scales with cell size in a wide range of cell types but the mechanisms determining overall nuclear size remain largely unknown. Here we investigate the role of ...

Background: integrity is essential for compartmentalisation of nucleus and cytoplasm. Importantly, mutations in -encoding genes are the second-highest cause of familial dilated cardiomyopathy. One ...

Implementation of the Dominant Attribute discretization and the LEM2 rule induction algorithms, using Python - Ruturaj4/Dominant-Attribute-discretization-and-the-LEM2-algorithm ...

A research team has found that inner nuclear membrane protein Lem2, backed up by endoplasmic reticulum protein Lnp1, acts as a valve to control the flow of the membrane into and out of the nuclear ...

Abstract: Rough Set Theory (RST), proposed by Z Pawlak, is a new mathematical model for uncertain data [2]. Tools based on RST are mainly useful for data mining tasks such as classification and rule ...

Transcriptionally silent chromatin often localizes to the nuclear periphery. However, whether the nuclear envelope (NE) is a site for post-transcriptional gene repression is not well understood. Here ...

In the interests of transparency, eLife publishes the most substantive revision requests and the accompanying author responses. The authors show that CDK1 phosphorylates Chmp7, after which Chmp7 is ...